There's a cute guy / girl sitting alone at the bar, just over from where you are. He / she catches your eye, so you decide to give it a try. What's your opening line?
You know the old saying, it takes less muscles to smile than it does to frown... Then you remove the hand wringing, the self flagellation, and the panicking, and add in the endorphins a smile brings, and yeah, happy's easier, and better than drugs!